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Structure paper

TitleCrystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor.
Journal, issue, pagesJ. Mol. Biol., Vol. 312, Page 743-751, Year 2001
Publish dateJul 3, 2001 (structure data deposition date)
AuthorsNar, H. / Werle, K. / Bauer, M.M. / Dollinger, H. / Jung, B.
External linksJ. Mol. Biol. / PubMed:11575929
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1jiz:
Crystal Structure Analysis of human Macrophage Elastase MMP-12
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-CGS:
N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / matrix metalloproteinase / MMP-12 / chronic obstructive pulmonary disease

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