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Structure paper

TitleCrystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 98, Page 9545-9550, Year 2001
Publish dateJun 11, 2001 (structure data deposition date)
AuthorsWhittington, D.A. / Waheed, A. / Ulmasov, B. / Shah, G.N. / Grubb, J.H. / Sly, W.S. / Christianson, D.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:11493685
MethodsX-ray diffraction
Resolution1.5 - 1.55 Å
Structure data

PDB-1jcz:
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-1jd0:
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII COMPLEXED WITH ACETAZOLAMIDE
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

ChemComp-AZM:
5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE / medication*YM

Source
  • homo sapiens (human)
KeywordsLYASE / Extracellular Domain / Human Carbonic Anhydrase XII / bitopic membrane protein / TYPE I MEMBRANE PROTEIN

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