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TitleStructural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole.
Journal, issue, pagesProtein Sci., Vol. 10, Page 2200-2206, Year 2001
Publish dateMay 23, 2001 (structure data deposition date)
AuthorsBattistutta, R. / De Moliner, E. / Sarno, S. / Zanotti, G. / Pinna, L.A.
External linksProtein Sci. / PubMed:11604527
MethodsX-ray diffraction
Resolution2.18 - 2.22 Å
Structure data

PDB-1j91:
Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the ATP-competitive inhibitor 4,5,6,7-tetrabromobenzotriazole
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

PDB-1jam:
Crystal structure of apo-form of Z. Mays CK2 protein kinase alpha subunit
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

Chemicals

ChemComp-TBS:
4,5,6,7-TETRABROMOBENZOTRIAZOLE

ChemComp-HOH:
WATER

Source
  • zea mays (maize)
KeywordsTRANSFERASE / CK2 / casein kinase 2 / inhibitors / tetrabromo-benzotriazole / protein kinase fold

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