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-Structure paper
Title | D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity |
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Journal, issue, pages | Chembiochem, Vol. 4, Page 181-185, Year 2003 |
Publish date | Dec 3, 2002 (structure data deposition date) |
Authors | Hansford, K.A. / Reid, R.C. / Clark, C.I. / Tyndall, J.D.A. / Whitehouse, M.W. / Guthrie, T. / McGeary, R.P. / Schafer, K. / Martin, J.L. / Fairlie, D.P. |
External links | Chembiochem / PubMed:12616631 |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.2 Å |
Structure data | PDB-1j1a: PDB-1kqu: |
Chemicals | ChemComp-CA: ChemComp-BHP: ChemComp-HOH: ChemComp-BR4: |
Source |
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Keywords | HYDROLASE / medicinal chemistry / enzyme inhibitor / structure-activity relationships / inflammation / Phospholipase A2 / Inhibitor |