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TitleCalorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 124, Page 205-215, Year 2002
Publish dateNov 2, 2001 (structure data deposition date)
AuthorsDavidson, J.P. / Lubman, O. / Rose, T. / Waksman, G. / Martin, S.F.
External linksJ. Am. Chem. Soc. / PubMed:11782172
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1is0:
Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rous sarcoma virus
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / conformationaly constrained INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex

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