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Structure paper

TitleConformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.
Journal, issue, pagesJ. Mol. Biol., Vol. 309, Page 423-435, Year 2001
Publish dateFeb 12, 2001 (structure data deposition date)
AuthorsSuresh, S. / Bressi, J.C. / Kennedy, K.J. / Verlinde, C.L. / Gelb, M.H. / Hol, W.G.
External linksJ. Mol. Biol. / PubMed:11371162
MethodsX-ray diffraction
Resolution2.6 - 3 Å
Structure data

PDB-1i32:
LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-1i33:
LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NMD:
N-NAPHTHALEN-1-YLMETHYL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE

ChemComp-HOH:
WATER

ChemComp-TND:
N-1,2,3,4-TETRAHYDRONAPHTH-1-YL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE

Source
  • leishmania mexicana (eukaryote)
KeywordsOXIDOREDUCTASE / enzyme / dehydrogenase

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