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-Structure paper
Title | ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 92, Page 2484-2488, Year 1995 |
Publish date | Jan 24, 1997 (structure data deposition date) |
Authors | Kempf, D.J. / Marsh, K.C. / Denissen, J.F. / McDonald, E. / Vasavanonda, S. / Flentge, C.A. / Green, B.E. / Fino, L. / Park, C.H. / Kong, X.P. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:7708670 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-1hxw: |
Chemicals | ChemComp-RIT: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / ASPARTYL PROTEASE / HYDROLASE / ASPARTIC PROTEINASE / HIV / HYDROLASE-HYDROLASE INHIBITOR complex |