+Search query
-Structure paper
Title | Rational design, synthesis, and crystallographic analysis of a hydroxyethylene-based HIV-1 protease inhibitor containing a heterocyclic P1'--P2' amide bond isostere. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 37, Page 3100-3107, Year 1994 |
Publish date | May 24, 1994 (structure data deposition date) |
Authors | Thompson, S.K. / Murthy, K.H. / Zhao, B. / Winborne, E. / Green, D.W. / Fisher, S.M. / DesJarlais, R.L. / Tomaszek Jr., T.A. / Meek, T.D. / Gleason, J.G. / Abdel-Meguid, S.S. |
External links | J. Med. Chem. / PubMed:7932533 |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | PDB-1hps: |
Chemicals | ChemComp-RUN: ChemComp-HOH: |
Source |
|
Keywords | HYDROLASE(ACID PROTEINASE) |