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Structure paper

TitleThe X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors
Journal, issue, pagesJ. Mol. Biol., Vol. 312, Page 133-, Year 2001
Publish dateJul 9, 2001 (structure data deposition date)
AuthorsErskine, P.T. / Newbold, R. / Brindley, A.A. / Wood, S.P. / Shoolingin-Jordan, P.M. / Warren, M.J. / Cooper, J.B.
External linksJ. Mol. Biol. / PubMed:11545591
MethodsX-ray diffraction
Resolution1.6 - 2 Å
Structure data

PDB-1h7n:
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1h7o:
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-1h7p:
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

PDB-1h7r:
SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SHF:
LAEVULINIC ACID

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-DAV:
DELTA-AMINO VALERIC ACID

ChemComp-KAH:
5-AMINO-4-HYDROXYHEXANOIC ACID

ChemComp-SHU:
4,6-DIOXOHEPTANOIC ACID

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsDEHYDRATASE / LYASE / ALDOLASE / TIM BARREL / TETRAPYRROLE SYNTHESIS

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