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Structure paper

TitleThe 1.76 A Resolution Crystal Structure of Glycogen Phosphorylase B Complexed with Glucose, and Cp320626, a Potential Antidiabetic Drug
Journal, issue, pagesBioorg. Med. Chem., Vol. 10, Page 1313-, Year 2002
Publish dateMay 25, 2001 (structure data deposition date)
AuthorsOikonomakos, N.G. / Zographos, S.E. / Skamnaki, V.T. / Archontis, G.
External linksBioorg. Med. Chem. / PubMed:11886794
MethodsX-ray diffraction
Resolution1.76 Å
Structure data

PDB-1h5u:
THE 1.76 A RESOLUTION CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE B COMPLEXED WITH GLUCOSE AND CP320626, A POTENTIAL ANTIDIABETIC DRUG
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

Chemicals

ChemComp-CHI:
5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsGLYCOGEN METABOLISM / GLYCOGEN PHOSPHORYLASE B / INHIBITION / CENTRAL CAVITY / DRUG BINDING SITE / TRANSFERASE

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