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-Structure paper
Title | Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer. |
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Journal, issue, pages | J. Biol. Chem., Vol. 277, Page 13155-13166, Year 2002 |
Publish date | Jan 14, 2002 (structure data deposition date) |
Authors | Dobritzsch, D. / Ricagno, S. / Schneider, G. / Schnackerz, K.D. / Lindqvist, Y. |
External links | J. Biol. Chem. / PubMed:11796730 |
Methods | X-ray diffraction |
Resolution | 1.65 - 3.3 Å |
Structure data | PDB-1gt8: PDB-1gte: PDB-1gth: |
Chemicals | ChemComp-SF4: ChemComp-FMN: ChemComp-FAD: ChemComp-NDP: ChemComp-UAA: ChemComp-IUR: ChemComp-HOH: ChemComp-IDH: ChemComp-URA: |
Source |
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Keywords | OXIDOREDUCTASE / ELECTRON TRANSFER / FLAVIN / IRON-SULFUR CLUSTERS / PYRIMIDINE CATABOLISM / 5-FLUOROURACIL DEGRADATION |