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Structure paper

TitleDesign of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.
Journal, issue, pagesBiochemistry, Vol. 33, Page 5745-5758, Year 1994
Publish dateJul 30, 2000 (structure data deposition date)
AuthorsWatson, K.A. / Mitchell, E.P. / Johnson, L.N. / Son, J.C. / Bichard, C.J. / Orchard, M.G. / Fleet, G.W. / Oikonomakos, N.G. / Leonidas, D.D. / Kontou, M. / Papageorgioui, A.
External linksBiochemistry / PubMed:8180201
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-1gg8:
DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-GLG:
ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-IMP:
INOSINIC ACID

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE / GLYCOGEN PHOSPHORYLASE / INHIBITOR COMPLEX / CATALYTIC SITE / DESIGN

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