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Structure paper

TitleCrystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors.
Journal, issue, pagesBiochemistry, Vol. 40, Page 5399-5406, Year 2001
Publish dateJan 26, 2000 (structure data deposition date)
AuthorsLi, H. / Raman, C.S. / Martasek, P. / Masters, B.S. / Poulos, T.L.
External linksBiochemistry / PubMed:11331003
MethodsX-ray diffraction
Resolution1.93 - 2.3 Å
Structure data

PDB-1ed6:
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-NIO (H4B FREE)
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-1foi:
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1400W(H4B-FREE)
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-1fol:
REDUCED BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG(H4B-FREE)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1foo:
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1fop:
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-BOUND)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-ZN:
Unknown entry

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-ILO:
N5-IMINOETHYL-L-ORNITHINE

ChemComp-CAD:
CACODYLIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CAC:
CACODYLATE ION

ChemComp-14W:
N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE

ChemComp-ARG:
ARGININE

ChemComp-NO:
NITRIC OXIDE

ChemComp-H4B:
5,6,7,8-TETRAHYDROBIOPTERIN / neurotransmitter*YM

Source
  • bos taurus (domestic cattle)
KeywordsOXIDOREDUCTASE / NITRIC OXIDE SYNTHASE / HEME PROTEIN / alpha-beta fold

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