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Structure paper

TitleStructure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Journal, issue, pagesScience, Vol. 290, Page 150-153, Year 2000
Publish dateAug 9, 2000 (structure data deposition date)
AuthorsHong, L. / Koelsch, G. / Lin, X. / Wu, S. / Terzyan, S. / Ghosh, A.K. / Zhang, X.C. / Tang, J.
External linksScience / PubMed:11021803
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1fkn:
Structure of Beta-Secretase Complexed with Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Alzheimer's disease / beta-secretase / memapsin 2 / BASE / aspartic protease / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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