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Structure paper

TitleC-H...O hydrogen bonds in the nuclear receptor RARgamma--a potential tool for drug selectivity.
Journal, issue, pagesStructure, Vol. 10, Page 1197-1204, Year 2002
Publish dateJul 19, 2000 (structure data deposition date)
AuthorsKlaholz, B. / Moras, D.
External linksStructure / PubMed:12220491
MethodsX-ray diffraction
Resolution1.38 Å
Structure data

PDB-1fd0:
ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARGAMMA-SELECTIVE RETINOID SR11254
Method: X-RAY DIFFRACTION / Resolution: 1.38 Å

Chemicals

ChemComp-254:
6-[HYDROXYIMINO-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALEN-2-YL)-METHYL]-NAPHTALENE-2-CARBOXYLIC ACID

ChemComp-LMU:
DODECYL-ALPHA-D-MALTOSIDE / detergent*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / isotype selectivity / retinoid ligand complexes / drug design / antiparallel alpha-helical sandwich fold / CH...O hydrogen bond / Structural Proteomics in Europe / SPINE / Structural Genomics

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