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-Structure paper
Title | Crystals of the urokinase type plasminogen activator variant beta(c)-uPAin complex with small molecule inhibitors open the way towards structure-based drug design. |
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Journal, issue, pages | J. Mol. Biol., Vol. 301, Page 465-475, Year 2000 |
Publish date | Jun 15, 2000 (structure data deposition date) |
![]() | Zeslawska, E. / Schweinitz, A. / Karcher, A. / Sondermann, P. / Sperl, S. / Sturzebecher, J. / Jacob, U. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.6 Å |
Structure data | ![]() PDB-1f5k: ![]() PDB-1f5l: ![]() PDB-1f92: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-BEN: ![]() ChemComp-HOH: ![]() ChemComp-AMR: ![]() ChemComp-UKP: |
Source |
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![]() | HYDROLASE / UROKINASE / INHIBITOR / SERINE PROTEASE / HUMAN |