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-Structure paper
Title | Site-directed ligand discovery. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 97, Page 9367-9372, Year 2000 |
Publish date | Jun 7, 2000 (structure data deposition date) |
Authors | Erlanson, D.A. / Braisted, A.C. / Raphael, D.R. / Randal, M. / Stroud, R.M. / Gordon, E.M. / Wells, J.A. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:10944209 |
Methods | X-ray diffraction |
Resolution | 1.75 - 2.15 Å |
Structure data | PDB-1f4b: PDB-1f4c: PDB-1f4d: PDB-1f4e: PDB-1f4f: PDB-1f4g: |
Chemicals | ChemComp-SO4: ChemComp-GOL: ChemComp-HOH: ChemComp-TP2: ChemComp-TPR: ChemComp-TP3: ChemComp-TP4: |
Source |
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Keywords | TRANSFERASE / E. coli thymidylate synthase / E. Coli Thymidylate Synthase Modified at Cysteine 146 / Crystal Structure of E. Coli Thymidylate Synthase C146S / L143C Covalently Modified at C143 with N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL / Crystal Structure of E. Coli Thymidylate Synthase Complexed with Tosyl-D-Proline / Crystal Structure of E. Coli Thymidylate Synthase Complexed with SP-722 / Crystal Structure of E. Coli Thymidylate Synthase Complexed with SP-876 |