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TitleCrystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.
Journal, issue, pagesJ. Biol. Chem., Vol. 275, Page 30610-30617, Year 2000
Publish dateMay 10, 2000 (structure data deposition date)
AuthorsPandit, J. / Danley, D.E. / Schulte, G.K. / Mazzalupo, S. / Pauly, T.A. / Hayward, C.M. / Hamanaka, E.S. / Thompson, J.F. / Harwood Jr., H.J.
External linksJ. Biol. Chem. / PubMed:10896663
MethodsX-ray diffraction
Resolution2.15 Å
Structure data

PDB-1ezf:
CRYSTAL STRUCTURE OF HUMAN SQUALENE SYNTHASE
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-IN0:
N-{2-[TRANS-7-CHLORO-1-(2,2-DIMETHYL-PROPYL) -5-NAPHTHALEN-1-YL-2-OXO-1,2,3,5-TETRAHYDRO-BENZO[E]

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / isoprenoid synthase fold / all alpha-helix

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