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TitleCrystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
Journal, issue, pagesJ. Mol. Biol., Vol. 302, Page 1193-1212, Year 2000
Publish dateMay 5, 2000 (structure data deposition date)
AuthorsBaca, A.M. / Sirawaraporn, R. / Turley, S. / Sirawaraporn, W. / Hol, W.G.
External linksJ. Mol. Biol. / PubMed:11007651
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-1eye:
1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PMM:
PTERIN-6-YL-METHYL-MONOPHOSPHATE

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsTRANSFERASE / alpha-beta barrel

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