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Structure paper

TitleCrystal Structure of Cruzain bound to WRR-112
Journal, issue, pagesTo be Published
Publish dateApr 26, 2000 (structure data deposition date)
AuthorsBrinen, L.S. / Gillmor, S.A. / Fletterick, R.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1ewm:
THE CYSTEINE PROTEASE CRUZAIN BOUND TO WRR-112
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-RL2:
N-[3-CARBOXY-2-HYDROXY-PROPIONYL]-L-HOMOPHENYLALANYL-AMINO-2-METHYLBUTANE

ChemComp-HOH:
WATER

Source
  • trypanosoma cruzi (eukaryote)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / cruzain / cruzipain / drug design / covalent inhibitor / cysteine protease / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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