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IF

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Structure paper

TitleDirect observation by X-ray analysis of the tetrahedral intermediate of aspartic proteinases.
Journal, issue, pagesProtein Sci., Vol. 1, Page 322-328, Year 1992
Publish dateJul 27, 1994 (structure data deposition date)
AuthorsVeerapandian, B. / Cooper, J.B. / Sali, A. / Blundell, T.L. / Rosati, R.L. / Dominy, B.W. / Damon, D.B. / Hoover, D.J.
External linksPubMed:1304340
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1epo:
ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-2Z3:
N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide

ChemComp-HOH:
WATER

Source
  • cryphonectria parasitica (chestnut blight fungus)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / ACID PROTEINASE / HYDROLASE-HYDROLASE INHIBITOR complex

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