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Structure paper

TitleStructural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors.
Journal, issue, pagesBiochemistry, Vol. 34, Page 3193-3203, Year 1995
Publish dateOct 24, 1994 (structure data deposition date)
AuthorsMattos, C. / Giammona, D.A. / Petsko, G.A. / Ringe, D.
External linksBiochemistry / PubMed:7880814
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1eld:
Structural analysis of the active site of porcine pancreatic elastase based on the x-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1ele:
STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-0Z0:
N-(trifluoroacetyl)-L-phenylalanyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide

ChemComp-CA:
Unknown entry

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

ChemComp-0QN:
N-(trifluoroacetyl)-L-valyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide

ChemComp-SO4:
SULFATE ION

Source
  • sus scrofa (pig)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / SERINE PROTEINASE

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