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TitleGuanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions.
Journal, issue, pagesBiochemistry, Vol. 39, Page 15055-15061, Year 2000
Publish dateFeb 14, 2000 (structure data deposition date)
AuthorsThorpe, J.H. / Hobbs, J.R. / Todd, A.K. / Denny, W.A. / Charlton, P. / Cardin, C.J.
External linksBiochemistry / PubMed:11106483
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1eg6:
CRYSTAL STRUCTURE ANALYSIS OF D(CG(5-BRU)ACG) COMPLEXES TO A PHENAZINE
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-3CO:
COBALT (III) ION

ChemComp-BR:
BROMIDE ION

ChemComp-BFA:
9-BROMO-PHENAZINE-1-CARBOXYLIC ACID (2-DIMETHYLAMINO-ETHYL)-AMIDE

ChemComp-HOH:
WATER

KeywordsDNA / DRUG-DNA COMPLEX / INTERCALATION / MAJOR GROOVE BINDING / DOUBLE HELIX

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