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Structure paper

TitleA thermodynamic and structural analysis of DNA minor-groove complex formation.
Journal, issue, pagesJ. Mol. Biol., Vol. 300, Page 321-337, Year 2000
Publish dateFeb 1, 2000 (structure data deposition date)
AuthorsMazur, S. / Tanious, F.A. / Ding, D. / Kumar, A. / Boykin, D.W. / Simpson, I.J. / Neidle, S. / Wilson, W.D.
External linksJ. Mol. Biol. / PubMed:10873468
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-1eel:
STRUCTURE OF A COMPLEX BETWEEN THE DNA SEQUENCE DCGCGAATTCGCG AND BIS[PIPERIDINO-ETHYL]-FURAMIDINE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-D24:
2,5-BIS-[4-[CYCLOPENTA-1,3-DIEN-5-YLAMINO-1-AMINOMETHYL]-PHEN-1-YL]FURAN

ChemComp-HOH:
WATER

KeywordsDNA / MINOR GROOVE BINDING LIGAND / B-DNA / BULKY SIDE-CHAINS

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