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-Structure paper
Title | Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles. |
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Journal, issue, pages | J. Med. Chem., Vol. 43, Page 2797-, Year 2000 |
Publish date | May 11, 2000 (structure data deposition date) |
![]() | Arris, C.E. / Boyle, F.T. / Calvert, A.H. / Curtin, N.J. / Endicott, J.A. / Garman, E.F. / Gibson, A.E. / Golding, B.T. / Grant, S. / Griffin, R.J. ...Arris, C.E. / Boyle, F.T. / Calvert, A.H. / Curtin, N.J. / Endicott, J.A. / Garman, E.F. / Gibson, A.E. / Golding, B.T. / Grant, S. / Griffin, R.J. / Jewsbury, P. / Johnson, L.N. / Lawrie, A.M. / Newell, D.R. / Noble, M.E.M. / Sausville, E.A. / Schultz, R. / Yu, W. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 1.95 Å |
Structure data | ![]() PDB-1e1v: ![]() PDB-1e1x: |
Chemicals | ![]() ChemComp-CMG: ![]() ChemComp-HOH: ![]() ChemComp-NW1: |
Source |
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![]() | PROTEIN KINASE / CELL CYCLE / PHOSPHORYLATION / CELL DIVISION / MITOSIS / INHIBITION |