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TitleStructure of Acetylcholinesterase Complexed with (-)-Galanthamine at 2.3A Resolution
Journal, issue, pagesFEBS Lett., Vol. 463, Page 321-, Year 1999
Publish dateDec 21, 1999 (structure data deposition date)
AuthorsGreenblatt, H.M. / Kryger, G. / Lewis, T.T. / Silman, I. / Sussman, J.L.
External linksFEBS Lett. / PubMed:10606746
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1dx6:
STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-GALANTHAMINE AT 2.3A RESOLUTION
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-GNT:
(-)-GALANTHAMINE / inhibitor, alkaloid*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • torpedo californica (Pacific electric ray)
KeywordsHYDROLASE / SERINE HYDROLASE / CHOLINESTERASE / ALZHEIMER'S DISEASE

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