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-Structure paper
Title | Crystal structure of the IMP-1 metallo beta-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxylate inhibitor: binding determinants of a potent, broad-spectrum inhibitor. |
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Journal, issue, pages | Biochemistry, Vol. 39, Page 4288-4298, Year 2000 |
Publish date | Nov 8, 1999 (structure data deposition date) |
![]() | Concha, N.O. / Janson, C.A. / Rowling, P. / Pearson, S. / Cheever, C.A. / Clarke, B.P. / Lewis, C. / Galleni, M. / Frere, J.M. / Payne, D.J. ...Concha, N.O. / Janson, C.A. / Rowling, P. / Pearson, S. / Cheever, C.A. / Clarke, B.P. / Lewis, C. / Galleni, M. / Frere, J.M. / Payne, D.J. / Bateson, J.H. / Abdel-Meguid, S.S. |
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Methods | X-ray diffraction |
Resolution | 2 - 3.1 Å |
Structure data | ![]() PDB-1dd6: ![]() PDB-1ddk: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-ZN: ![]() ChemComp-MCI: ![]() ChemComp-HOH: ![]() ChemComp-ACY: |
Source |
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![]() | HYDROLASE / METALLO BETA-LACTAMASE INHIBITOR / MERCAPTOCARBOXYLATE INHIBITOR / IMP-1 METALLO BETA-LACTAMASE / BINUCLEAR METAL CENTER / ZN BETA-LACTAMASE |