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Structure paper

TitleProtein-nucleotide interactions in E. coli DNA topoisomerase I.
Journal, issue, pagesNat. Struct. Biol., Vol. 6, Page 961-968, Year 1999
Publish dateAug 31, 1999 (structure data deposition date)
AuthorsFeinberg, H. / Changela, A. / Mondragon, A.
External linksNat. Struct. Biol. / PubMed:10504732
MethodsX-ray diffraction
Resolution2.3 - 2.55 Å
Structure data

PDB-1cy0:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 3'-5'-ADENOSINE DIPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-1cy1:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'PTPTPT
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1cy2:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH TPTPTP3'
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1cy4:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'pTpTpTp3'
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-1cy6:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 3' THYMIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1cy7:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'-THYMIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1cy8:
COMPLEX OF E.COLI DNA TOPOISOMERASE I WITH 5'-THYMIDINE MONOPHOSPHATE AND 3'-THYMIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-A3P:
ADENOSINE-3'-5'-DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-THP:
THYMIDINE-3',5'-DIPHOSPHATE

ChemComp-T3P:
THYMIDINE-3'-PHOSPHATE

Source
  • escherichia coli (E. coli)
KeywordsISOMERASE / DNA TOPOISOMERASE / RELAXING ENZYME

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