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Structure paper

TitleStructural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
Journal, issue, pagesJ. Mol. Biol., Vol. 295, Page 557-567, Year 2000
Publish dateAug 24, 1999 (structure data deposition date)
AuthorsKielkopf, C.L. / Bremer, R.E. / White, S. / Szewczyk, J.W. / Turner, J.M. / Baird, E.E. / Dervan, P.B. / Rees, D.C.
External linksJ. Mol. Biol. / PubMed:10623546
MethodsX-ray diffraction
Resolution2.15 - 2.27 Å
Structure data

PDB-1cvx:
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYHPPYBETADP)2 BOUND TO B-DNA DECAMER CCAGATCTGG
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

PDB-1cvy:
CRYSTAL STRUCTURE OF POLYAMIDE DIMER (IMPYPYPYBETADP)2 BOUND TO CCAGATCTGG
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-HP2:
HYDROXYPYRROLE-IMIDAZOLE-PYRROLE POLYAMIDE

ChemComp-HOH:
WATER

ChemComp-IPY:
IMIDAZOLE-PYRROLE POLYAMIDE

KeywordsDNA / POLYAMIDE / MINOR GROOVE RECOGNITION / TA RECOGNITION / DOUBLE DRUG IN MINOR GROOVE / IMIDAZOLE-PYRROLE POLYAMIDE

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