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-Structure paper
Title | New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. |
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Journal, issue, pages | Biochemistry, Vol. 38, Page 16783-16793, Year 1999 |
Publish date | Jul 26, 1999 (structure data deposition date) |
Authors | Greasley, S.E. / Yamashita, M.M. / Cai, H. / Benkovic, S.J. / Boger, D.L. / Wilson, I.A. |
External links | Biochemistry / PubMed:10606510 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-1c2t: PDB-1c3e: |
Chemicals | ChemComp-NHS: ChemComp-GAR: ChemComp-HOH: ChemComp-NHR: |
Source |
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Keywords | TRANSFERASE / PURINE BIOSYNTHESIS / ANTI-CANCER AGENT / INHIBITOR COMPLEX |