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Structure paper

TitleCrystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.
Journal, issue, pagesBiochemistry, Vol. 36, Page 11205-11215, Year 1997
Publish dateApr 11, 1997 (structure data deposition date)
AuthorsSawaya, M.R. / Prasad, R. / Wilson, S.H. / Kraut, J. / Pelletier, H.
External linksBiochemistry / PubMed:9287163
MethodsX-ray diffraction
Resolution2.2 - 2.6 Å
Structure data

PDB-1bpx:
DNA POLYMERASE BETA/DNA COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1bpy:
HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1bpz:
HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-DCT:
2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / NUCLEOTIDYLTRANSFERASE / DNA REPAIR / BASE EXCISION REPAIR PATHWAY / TRANSFERASE-DNA COMPLEX

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