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Structure paper

TitleStructure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis.
Journal, issue, pagesJ. Mol. Biol., Vol. 234, Page 165-178, Year 1993
Publish dateSep 30, 1993 (structure data deposition date)
AuthorsChen, C.C. / Rahil, J. / Pratt, R.F. / Herzberg, O.
External linksJ. Mol. Biol. / PubMed:8230196
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1blh:
STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FOS:
[[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
KeywordsHYDROLASE(BETA-LACTAMASE)

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