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TitleStructure-Based Design of a Novel Series of Nonpeptide Ligands that Bind to the Pp60Src Sh2 Domain
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 119, Page 12471-, Year 1997
Publish dateMay 2, 1997 (structure data deposition date)
AuthorsHolland, D.R. / Lunney, E.A. / Plummer, M.S. / Mueller, W.T. / Mcconnell, P. / Pavlovsky, A. / Para, K.S. / Shahripour, A. / Humblet, C. / Sawyer, T.K. / Rubin, J.R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1bkm:
COCRYSTAL STRUCTURE OF D-AMINO ACID SUBSTITUTED PHOSPHOPEPTIDE COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-1C5:
[[O-PHOSPHONO-N-ACETYL-TYROSINYL]-GLUTAMYL-3[CYCLOHEXYLMETHYL]ALANINYL]-AMINE

ChemComp-HOH:
WATER

Source
  • rous sarcoma virus
KeywordsTRANSFORMING PROTEIN / V-SRC SH2 DOMAIN / PHOSPHOTYROSINE RECOGNITION DOMAIN / PP60 SRC SH2 DOMAIN / TRIPEPTIDE / D-AMINO ACID

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