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Structure paper

TitleCatalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography.
Journal, issue, pagesBiochemistry, Vol. 38, Page 7265-7272, Year 1999
Publish dateFeb 22, 1999 (structure data deposition date)
AuthorsGonin, P. / Xu, Y. / Milon, L. / Dabernat, S. / Morr, M. / Kumar, R. / Lacombe, M.L. / Janin, J. / Lascu, I.
External linksBiochemistry / PubMed:10353838
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1b99:
3'-FLUORO-URIDINE DIPHOSPHATE BINDING TO NUCLEOSIDE DIPHOSPHATE KINASE
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-FUP:
2',3'-DIDEOXY-3'-FLUORO-URIDIDINE-5'-DIPHOSPHATE

ChemComp-POP:
PYROPHOSPHATE 2-

ChemComp-HOH:
WATER

Source
  • dictyostelium discoideum (eukaryote)
KeywordsTRANSFERASE / PHOSPHOTRANSFERASE / ANTIVIRAL AGENT / FLUOROURIDINE

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