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Structure paper

TitleStructure of human methionine aminopeptidase-2 complexed with fumagillin.
Journal, issue, pagesScience, Vol. 282, Page 1324-1327, Year 1998
Publish dateJan 13, 1999 (structure data deposition date)
AuthorsLiu, S. / Widom, J. / Kemp, C.W. / Crews, C.M. / Clardy, J.
External linksScience / PubMed:9812898
MethodsX-ray diffraction
Resolution1.6 - 1.8 Å
Structure data

PDB-1b59:
COMPLEX OF HUMAN METHIONINE AMINOPEPTIDASE-2 COMPLEXED WITH OVALICIN
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1b6a:
HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1bn5:
HUMAN METHIONINE AMINOPEPTIDASE 2
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1boa:
HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH ANGIOGENESIS INHIBITOR FUMAGILLIN
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-CO:
Unknown entry

ChemComp-OVA:
3,4-DIHYDROXY-2-METHOXY-4-METHYL-3-[2-METHYL-3-(3-METHYL-BUT-2-ENYL) -OXIRANYL]-CYCLOHEXANONE

ChemComp-HOH:
WATER

ChemComp-TN4:
(1R,2S,3S,4R)-4-hydroxy-2-methoxy-4-methyl-3-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl

ChemComp-TBU:
TERTIARY-BUTYL ALCOHOL

ChemComp-FUG:
FUMAGILLIN / Antimicrobial*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ANGIOGENESIS INHIBITOR / AMINOPEPTIDASE / METHIONINE AMINOPEPTIDASE / FUMAGILLIN

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