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TitleBinding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.
Journal, issue, pagesEur. J. Biochem., Vol. 263, Page 646-655, Year 1999
Publish dateNov 12, 1998 (structure data deposition date)
AuthorsYang, X.L. / Kaenzig, C. / Lee, M. / Wang, A.H.
External linksEur. J. Biochem. / PubMed:10469127
MethodsNMR (solution)
Structure data

PDB-1b0s:
BINDING OF AR-1-144, A TRI-IMIDAZOLE DNA MINOR GROOVE BINDER, TO CCGG SEQUENCE ANALYZED BY NMR SPECTROSCOPY
Method: SOLUTION NMR

Chemicals

ChemComp-AR1:
(2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1

KeywordsDNA / ANTICANCER DRUG / DRUG DESIGN / DNA STRUCTURE / SEQUENCE SPECIFIC RECOGNITION

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