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TitleActive-site mobility in human immunodeficiency virus, type 1, protease as demonstrated by crystal structure of A28S mutant.
Journal, issue, pagesProtein Sci., Vol. 7, Page 300-305, Year 1998
Publish dateOct 13, 1997 (structure data deposition date)
AuthorsHong, L. / Hartsuck, J.A. / Foundling, S. / Ermolieff, J. / Tang, J.
External linksPubMed:9521105
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1axa:
ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-U0E:
N-[[1-[N-ACETAMIDYL]-[1-CYCLOHEXYLMETHYL-2-HYDROXY-4-ISOPROPYL]-BUT-4-YL]-CARBONYL]-GLUTAMINYL-ARGINYL-AMIDE

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsASPARTYL PROTEASE / HIV PROTEASE / MUTANT / ASPARTIC PROTEASE / HYDROLASE / ACID PROTEINASE

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