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Title | A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. |
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Journal, issue, pages | Structure, Vol. 5, Page 601-612, Year 1997 |
Publish date | Apr 11, 1997 (structure data deposition date) |
![]() | Urzhumtsev, A. / Tete-Favier, F. / Mitschler, A. / Barbanton, J. / Barth, P. / Urzhumtseva, L. / Biellmann, J.F. / Podjarny, A. / Moras, D. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.3 Å |
Structure data | ![]() PDB-1ah0: ![]() PDB-1ah3: ![]() PDB-1ah4: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-SBI: ![]() ChemComp-HOH: ![]() ChemComp-TOL: |
Source |
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![]() | OXIDOREDUCTASE / SORBINIL INHIBITOR / DIABETES / ALDOSE REDUCTASE / INHIBITION |