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-Structure paper
Title | Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors. |
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Journal, issue, pages | J. Biol. Chem., Vol. 272, Page 21713-21719, Year 1997 |
Publish date | Feb 17, 1998 (structure data deposition date) |
Authors | Renatus, M. / Bode, W. / Huber, R. / Sturzebecher, J. / Prasa, D. / Fischer, S. / Kohnert, U. / Stubbs, M.T. |
External links | J. Biol. Chem. / PubMed:9268299 |
Methods | X-ray diffraction |
Resolution | 2.9 Å |
Structure data | PDB-1a5h: |
Chemicals | ChemComp-BBA: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / TRYPSIN LIKE SERINE PROTEASE / FIBRINOLYTIC ENZYME |