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Structure paper

TitleHuman beta-tryptase is a ring-like tetramer with active sites facing a central pore.
Journal, issue, pagesNature, Vol. 392, Page 306-311, Year 1998
Publish dateDec 3, 1997 (structure data deposition date)
AuthorsPereira, P.J. / Bergner, A. / Macedo-Ribeiro, S. / Huber, R. / Matschiner, G. / Fritz, H. / Sommerhoff, C.P. / Bode, W.
External linksNature / PubMed:9521329
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1a0l:
HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-APA:
(2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / TRYPSIN-LIKE SERINE PROTEINASE / TETRAMER / HEPARIN / ALLERGY / ASTHMA / SERINE PROTEINASE / HYDROLASE-HYDROLASE INHIBITOR complex

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