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Structure paper

TitleMolecular basis of DNA polymerase zeta's reverse transcriptase activity
Journal, issue, pagesNat Commun, Year 2026
Publish dateMar 11, 2026 (structure data deposition date)
AuthorsMalik R / Johnson RE / Prakash L / Prakash S / Aggarwal AK
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution3.03 Å
Structure data

76020

11ss

EMDB-76020, PDB-11ss:
Cryo-EM structure of DNA polymerase Zeta with RNA:DNA hybrid and incoming dNTP
Method: EM (single particle) / Resolution: 3.03 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-DCP:
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA/RNA / Protein complex / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA-RNA complex

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