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Structure paper

TitleStructural Insights into RNA Phosphorylation by the RNase PNK Module of the Human Rixosome Complex.
Journal, issue, pagesTo Be Published
Publish dateFeb 3, 2026 (structure data deposition date)
AuthorsGordon J / Stanley RE
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.35 - 3.6 Å
Structure data

75411

10rn

EMDB-75411, PDB-10rn:
Human RNase PNK bound to ATPyS ligand
Method: EM (single particle) / Resolution: 3.6 Å

75414

10rr

EMDB-75414, PDB-10rr:
Human RNase PNK bound to AMPPNP ligand + rCAA in PNK active site
Method: EM (single particle) / Resolution: 3.5 Å

EMDB-75415: PDB 10RN EMD-75411 Human RNase PNK bound to ATPyS ligand consensus EM map
Method: EM (single particle) / Resolution: 3.6 Å

EMDB-75416: PDB 10RN EMD-75411 Human RNase PNK bound to ATPyS ligand focused EM map
Method: EM (single particle) / Resolution: 3.5 Å

EMDB-75418: PDB 10RR EMD-75414 Human RNase PNK bound to AMPPNP ligand + rCAA in PNK active site consensus EM map
Method: EM (single particle) / Resolution: 3.43 Å

EMDB-75419: PDB 10RR EMD-75414 Human RNase PNK bound to AMPPNP ligand + rCAA in PNK active site focused EM map
Method: EM (single particle) / Resolution: 3.35 Å

Chemicals

ChemComp-AGS:
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Ribonuclease / Kinase / HEPN / LAS1L / NOL9 / ITS2 / Rixosome / RNA

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