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Structure paper

TitleStructural basis for the synaptic adhesion protein ELFN1-mediated modulation of mGlu7
Journal, issue, pagesTo be published
Publish dateApr 17, 2026 (structure data deposition date)
AuthorsLin S / Feng Y / Shui S / Chen M / Chu X / Yi C / Han S / Zhao Q / Wu B
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 - 4.0 Å
Structure data

80373

25tv

EMDB-80373, PDB-25tv:
Cryo-EM structure of the 2:1 mGlu7-ELFN1 complex
Method: EM (single particle) / Resolution: 3.8 Å

80374

25tw

EMDB-80374, PDB-25tw:
Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation D
Method: EM (single particle) / Resolution: 3.5 Å

80375

25tx

EMDB-80375, PDB-25tx:
Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation C
Method: EM (single particle) / Resolution: 4.0 Å

80376

25ty

EMDB-80376, PDB-25ty:
Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation B
Method: EM (single particle) / Resolution: 3.6 Å

80380

25uj

EMDB-80380, PDB-25uj:
Cryo-EM structure of the 2:2 mGlu7-ELFN1 complex in conformation A
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GLU:
GLUTAMIC ACID

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / GPCR / Metabotropic glutamate receptor / ELFN1

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