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TitleBROADLY REACTIVE HUMAN MONOCLONAL ANTIBODY TARGETING CONSERVED PNEUMOCOCCAL CHOLINE BINDING DOMAIN INCREASES PROTECTION AGAINST LETHAL PNEUMOCOCCAL INFECTION
Journal, issue, pagesTo Be Published
Publish dateApr 15, 2026 (structure data deposition date)
AuthorsMcCormick A / Ghazi Esfahani B / Vida J / Lee FE / Tompkins M / McCaffrey K / Mousa J
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.35 - 3.7 Å
Structure data

76684

12qj

EMDB-76684, PDB-12qj:
Pneumococcal choline binding CbpE surface protein bounds to 5992-2 Fab
Method: EM (single particle) / Resolution: 3.35 Å

EMDB-76685: Pneumococcal choline binding CbpE surface protein bounds to multiple 5992-2 Fabs
Method: EM (single particle) / Resolution: 3.7 Å

Source
  • homo sapiens (human)
  • streptococcus pneumoniae (bacteria)
KeywordsIMMUNE SYSTEM / PNEUMOCOCCAL CHOLINE BINDING / CryoEM / HUMAN MONOCLONAL ANTIBODY

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