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-Structure paper
| Title | Engineered Cas9 complexes establish an experimentally grounded benchmark for heterogeneous cryo-EM reconstruction methods |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Apr 2, 2026 (structure data deposition date) |
 Authors | Grassetti AV / Kinman LF / Davis JH |
 External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.33 - 3.09 Å |
| Structure data |  EMDB-76391: Cryo-EM structure of dCas9 bound to DNA duplex with mixed extension lengths (2-14 bp)  EMDB-76392: Cryo-EM structure of dCas9 bound to DNA duplex with mixed extension lengths (2/8/14 bp)  EMDB-76393: Cryo-EM structure of dCas9 bound to DNA duplex, Rec3 domain resolved  EMDB-76394: Cryo-EM structure of dCas9 bound to DNA duplex, HNH domain resolved  EMDB-76395: Cryo-EM structure of dCas9 bound to DNA duplex with 14 bp extension  EMDB-76396: Cryo-EM structure of dCas9 bound to DNA duplex with 13 bp extension  EMDB-76397: Cryo-EM structure of dCas9 bound to DNA duplex with 12 bp extension  EMDB-76398: Cryo-EM structure of dCas9 bound to DNA duplex with 11 bp extension  EMDB-76399: Cryo-EM structure of dCas9 bound to DNA duplex with 10 bp extension  EMDB-76400: Cryo-EM structure of dCas9 bound to DNA duplex with 9 bp extension  EMDB-76401: Cryo-EM structure of dCas9 bound to DNA duplex with 8 bp extension  EMDB-76402: Cryo-EM structure of dCas9 bound to DNA duplex with 7 bp extension  EMDB-76403: Cryo-EM structure of dCas9 bound to DNA duplex with 6 bp extension  EMDB-76404: Cryo-EM structure of dCas9 bound to DNA duplex with 5 bp extension  EMDB-76405: Cryo-EM structure of dCas9 bound to DNA duplex with 4 bp extension  EMDB-76406: Cryo-EM structure of dCas9 bound to DNA duplex with 3 bp extension  EMDB-76407: Cryo-EM structure of dCas9 bound to DNA duplex with 2 bp extension |
| Source |
|
Streptococcus pyogenes M1 GAS (bacteria)