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TitleMultivalent Interactions Mediate SNAIL Transcription Factor Stimulation of the Nucleosome Deacetylase Activity of the CoREST Complex
Journal, issue, pagesTo Be Published
Publish dateFeb 17, 2026 (structure data deposition date)
AuthorsNam E / Osorio Valeriano M / Wang ZA / Whedon SD / Jiang H / Xinran Zhang M / Dubois-Coyne S / Haque IA / Jiang J / Ferreira J ...Nam E / Osorio Valeriano M / Wang ZA / Whedon SD / Jiang H / Xinran Zhang M / Dubois-Coyne S / Haque IA / Jiang J / Ferreira J / Farnung L / Lee K / Cole PA
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.3 - 4.2 Å
Structure data

EMDB-75624: SNAIL-GB1-LHC-Nucleosome complex (E-box in linker region)
Method: EM (single particle) / Resolution: 3.3 Å

EMDB-75625: SNAIL-GB1-LHC-Nucleosome complex (E-box in entry site)
Method: EM (single particle) / Resolution: 4.2 Å

Source
  • Homo sapiens environmental sample (environmental samples)
  • Xenopus laevis (African clawed frog)
  • Homo sapiens (human)

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