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Structure paper

TitleMechanisms of VEGFR2 activation by VEGF, neuropilin and heparin
Journal, issue, pagesTo Be Published
Publish dateFeb 3, 2026 (structure data deposition date)
AuthorsChen L / Bai X / Zhang X
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.34 - 3.65 Å
Structure data

75407

10ri

EMDB-75407, PDB-10ri:
Dimeric complex of VEGF, VEGFR2 and Neuropilin 1
Method: EM (single particle) / Resolution: 3.6 Å

75408

10rj

EMDB-75408, PDB-10rj:
Heparin-induced cis tetrameric complex of VEGF, VEGFR2 and Neuropilin 1
Method: EM (single particle) / Resolution: 3.34 Å

75409

10rk

EMDB-75409, PDB-10rk:
Heparin-induced trans tetrameric complex of VEGF, VEGFR2 and Neuropilin 1
Method: EM (single particle) / Resolution: 3.65 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

Source
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / VEGF / VEGFR / neuropilin / heparin

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