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TitleHuman NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
Journal, issue, pagesTo Be Published
Publish dateJan 23, 2026 (structure data deposition date)
AuthorsWang J / Man W / Xiao L / Du G / Chen M / Magupalli VG / Dahlberg PD / Wu H / Jensen GJ
External linksSearch PubMed
MethodsEM (tomography)
Structure data

EMDB-75244: Cryo-tomogram of a patch-like NLRP3 inflammasome condensate at the MTOC
Method: EM (tomography)


EMDB entry, No image

EMDB-75245: Cryo-tomogram of a solid-like NLRP3 inflammasome condensate at the MTOC
Method: EM (tomography)

EMDB-75246: Cryo-tomogram of the MTOC in human THP-1 cells
Method: EM (tomography)

EMDB-75247: Cryo-tomogram of a matured NLRP3 inflammasome condensate at the MTOC
Method: EM (tomography)

EMDB-75248: Cryo-tomogram of the MTOC in LPS-treated human THP-1 cells
Method: EM (tomography)

EMDB-75249: Cryo-tomogram of NLRP3-associated vesicles residing at the Golgi following LPS treatment
Method: EM (tomography)

EMDB-75250: Patch-like NLRP3 inflammasome condensate formed above or below the MTOC
Method: EM (tomography)

Source
  • Human THP-1 cells (human)

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