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Structure paper

TitleCryo-EM reveals that tRNA-transglycosylase enzymes from E. coli and Shigella can bind and act upon two tRNAs
Journal, issue, pagesTo Be Published
Publish dateJan 15, 2026 (structure data deposition date)
AuthorsHarjung A / Devaraj N
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.72 - 3.52 Å
Structure data

75124

10fa

EMDB-75124, PDB-10fa:
E. coli tRNA guanine transgylcosylase
Method: EM (single particle) / Resolution: 3.52 Å

75125

10fb

EMDB-75125, PDB-10fb:
E. coli TGT covalent intermediate with 1 tRNA
Method: EM (single particle) / Resolution: 3.01 Å

75126
EMDB Unreleased entry

10fc

EMDB-75126, PDB-10fc:
E. coli TGT covalent intermediate with 2 tRNAs
Method: EM (single particle) / Resolution: 2.72 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-9DG:
9-DEAZAGUANINE

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / TGT / RNA modifying enzyme / TRANSFERASE/RNA / TRANSFERASE-RNA complex

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