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Structure paper

TitleEnhanced Priming Leads to Rapid Induction of Broadly Neutralizing HIV-1 Apex Antibodies
Journal, issue, pagesTo Be Published
Publish dateDec 21, 2025 (structure data deposition date)
AuthorsRoark RS / Shapiro L / Kwong PD
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.9 - 3.3 Å
Structure data

74654

9zrx

EMDB-74654, PDB-9zrx:
Cryo-EM structure of SHIV-elicited CE79-1571 Fab in complex with HIV Env trimer Q23-SCT27
Method: EM (single particle) / Resolution: 3.3 Å

74655

9zry

EMDB-74655, PDB-9zry:
Cryo-EM structure of SHIV-elicited CN81-2029 Fab in complex with HIV Env trimer Q23-SCT27
Method: EM (single particle) / Resolution: 2.9 Å

74656

9zrz

EMDB-74656, PDB-9zrz:
Cryo-EM structure of SHIV-elicited CI93-1365 Fab in complex with HIV Env trimer Q23-SCT27
Method: EM (single particle) / Resolution: 2.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • macaca mulatta (Rhesus monkey)
  • human immunodeficiency virus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Neutralizing antibody / HIV V2 apex / SHIV-elicited / Immune complex / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / SHIV / neutralization

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